June 09, 2020

Nolan receives NIH/NCI grant

Timiya S. Nolan Headshot

COLUMBUS, OH— The National Institutes of Health/National Cancer Institute (NIH/NCI) has awarded a five-year career development grant to Principal Investigator Timiya S. Nolan, PhD, APRN-CNP, ANP-BC, assistant professor in the College of Nursing’s Martha S. Pitzer Center for Women, Children and Youth and her team to fund the study, “Piloting Y-AMBIENT: A Quality of Life Intervention for Young African American Breast Cancer Survivors in Treatment.”

Mentors on the study, all from Ohio State, include: Darryl D. Hood, PhD, College of Public Health; Electra D. Paskett, PhD, College of Medicine; Barbara Andersen, PhD, College of Psychology; Maryam Lustberg, MD, MPH, The James Comprehensive Cancer Center; and Alai Tan, PhD, College of Nursing. Mentors will guide Nolan in her pursuit of building an independent program of research that identifies contextual factors of quality of life (QOL) among young (18-44) breast cancer survivors from underrepresented minority groups.

In addition to training, this grant will support a study aimed at evaluating processes and preliminary outcomes of a targeted QOL intervention compared to enhanced usual care intervention in young African American (AA) cancer survivors who are receiving treatment for early (I-II) and late (III) stage breast cancer.

In this study, Nolan and her team will recruit and randomize 40 young AA breast cancer survivors who are in primary breast cancer treatment to an intervention group. This population is targeted given their general report of poorer QOL and more negative social determinants of health (e.g., low socioeconomic status, limited access to care, discrimination) than young White survivors.

The team will triangulate qualitative and quantitative responses from each participant to identify perceptions of the study’s feasibility and acceptability, chiefly measured by willingness to participate and the use of self-management strategies prescribed in the interventions. The team will also examine health-related outcomes (i.e., QOL, spiritual well-being, self-efficacy and social support) within and between intervention groups.

Upon completion of the study, the team will look to perform a larger, randomized controlled trial to determine efficacy and translate its findings to inform the development, implementation and dissemination/translation of multi-level QOL interventions and policy changes.

“This grant is building the foundation of my research career aimed at building healthy communities,” said Nolan. “My Y-AMBIENT intervention was adapted by applying the voices and stories of young AA breast cancer survivors. This pilot study will give us an indication of how my targeted intervention compares to enhanced usual care in these women, showing us the way forward to reduce disparities in cancer survivorship.”

“I’m ecstatic and honored to be trusted with this award,” said Nolan. “We at The Ohio State University believe that everyone deserves their best chance at living and living well, and ultimately this training and study will give me the tools to play my part as the change agent who helps cancer survivors attain wellness in their ‘new normal.’”   

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